Is Azar the antidote to the opioid crisis?
At a peak of the Durham heroin crisis last year, and as part of my EMS continuing education, we reviewed our protocol for delivering naloxone—a drug intended for emergency opioid overdose reversal. In Naloxone, and as with many antidotes, the problem is part of the solution. The agent’s active ingredient is a deactivated piece of the opioid, which fits snugly into the patient’s receptors and shuts out the problematic drug. But delivering naloxone is sensitive. As one paramedic explained, if you deliver too much of the antidote at once, patients will shoot straight out of their slumber “and punch you in the face!”