Fourth Quarter (Duke 20, Virginia Tech 41): Virginia Tech utilized its stifling defense and big play capability to dominate the fourth quarter and finish off the Blue Devils. After punting the ball away to the Hokies at the start of the quarter, Duke forced a quick three-and-out and took over at its own 35. After moving the ball all the way to the Virginia Tech 40, two dropped passes brought up a 4th and 11. A defensive pass interference call on the Hokies kept the Duke drive alive, and the Blue Devils took the ball all the way to the Virginia Tech seven yard line before coming up short on 4th down. On Virginia Tech's first play of the next drive, J.C. Coleman sprinted 86 yards for his second touchdown run of the day. The Blue Devil offense took over with just under ten minutes to go and trailing by three scores. With just under five minutes left, the Hokies stripped Sean Renfree in the pocket and recovered the fumble, ending Duke's chances of victory in Blacksburg.

Third Quarter (Duke 20, Virginia Tech 34): Much like the second, the third quarter was all Virginia Tech. The Hokies turned a three-point deficit into a 14-lead as Duke seemed to all but give up, exhibiting none of the energy they possessed in the first quarter.  Virginia Tech scored on their first two possessions with drives of 78 and 83 yards, culminating in touchdowns on a 45-yard run by J.C. Coleman and a 47-yard touchdown pass from Logan Thomas to Marcus Davis, respectively. Duke, on the other hand, lost 14 yards on offense in the quarter and went failed to pick up a first down on any three of their possessions. Virginia Tech added a 41-yard field goal from Cody Journell on their third and final possession of the quarter.

Second Quarter (Duke 20, Virginia Tech 17): Miscues on both sides of the ball sapped Duke's momentum in the second quarter and allowed the Hokies to cut the lead to three. Duke's first possession resulted in their only punt of the half but stuck the Hokies inside their own twenty. A promising Virginia Tech drive stalled in Duke territory, and a failed fourth down conversion gave the Blue Devils good field possession. With Boone and Renfree continuing to share time under center, Duke's offense failed to convert a fourth down conversion on the Hokie 44-yard line when Boone's deep pass was intercepted by Virginia Tech. Back-to-back dropped passes at the end of a 11-play, 66-yard drive forced Virginia Tech to settle for a 37-yard field goal on the ensuing possession. After the Blue Devils took over possession with 2:15 left in the half, another interception, this time thrown by Renfree, killed what had been a nearly textbook two-minute drill by the Duke offense. Virginia Tech's Detrick Bonner came down with the deflected pass and returned the ball 39 yards, setting up a 42-yard touchdown pass by Logan Thomas to a wide open receiver on the next play.

First Quarter (Duke 20, Virginia Tech 7): Several big plays from both teams resulted in a high-scoring first quarter, with Duke jumping out the early lead. Duke's offense took the field first with Sean Renfree starting under center after missing last week's game due to injury. The Blue Devils advanced slowly up the field before Renfree found Jamison Crowder deep over the middle for a 62-yard touchdown. Two consecutive punts by Virginia Tech resulted in six points for Duke, with Ross Martin nailing field goals of 40 and 23 yards.  On the second play of the ensuing Hokie drive, a bobbled pass intended for Gregory was intercepted by Jordan Byas, who returned twenty yards for the score. Virginia Tech responded, however, stringing together a solid drive to get on the board just before the end of the quarter. A 40-yard reception by Marcus Davis set up the four-yard touchdown run off left tackle for the score.